Research InterestsCardiovascular health; Fainting; High altitude
In addition to the well-known motor and sensory consequences of spinal cord injury (SCI), cardiovascular pathways can also be affected, which can cause life-threatening problems in cardiovascular control. In fact, a leading cause of mortality in SCI patients is cardiovascular disease. Through her research, Dr. Claydon hopes to shed light on the mechanisms underlying cardiovascular dysfunction after SCI.
Dr. Claydon also studies the patterns of cardiovascular adaptation that occur in response to permanent residence at high altitude. These studies have important implications for the millions of people who live and work at high altitude.
Another area of interest concerns the mechanisms underlying fainting spells, where affected individuals experience unexplained loss of consciousness, and their optimal treatment and management.
Dr. Claydon is an Associate Professor in the Department of Biomedical Physiology and Kinesiology at Simon Fraser University. She is also a Principal Investigator at ICORD.
Affiliation with organizations and societies:
- American Spinal Injury Association (ASIA)
- American Autonomic Society
- Physiological Society
Some of Dr. Claydon’s recent major awards and accomplishments include:
- Travel Award (Physiological Society, 2011)
- New Investigator Award (Heart & Stroke Foundation of Canada, 2009)
- Best Paper Award for Excellence in Spinal Cord Injury (ASIA, 2006)
- Best Poster Award (American Paraplegia Society, 2005)
- Post-Doctoral Fellowship (Rick Hansen Man in Motion Research Foundation, 2005)
- Post-Doctoral Fellowship (National Health Services, 2001)
Current Lab Members
|M.Sc. Students||Ph.D. Students||Research Staff|
|Vera-Ellen Lucci||Maureen McGrath|
|Matthew Dorton||Janelle Pennington|
|Natalie Heeney||Brooke Hockin|
Recent graduates include: Esther Maas (M.Sc.), Matthew Lloyd (Ph.D.)
|Kimiya Sabbaghan||Poster Presentation Award at the Biomedical Physiology & Kinesiology 6th Annual Research Day (Simon Fraser University)|
|2010||Anastasia Dikareva||Best Poster by an undergraduate student (Disabilities Health Research Network)|
|Indejeet Sahota||Best poster by a master’s student (Disabilities Health Research Network)|
|2009||Inderjeet Sahota||Graduate Fellowship (Simon Fraser University)|
Current Opportunities in the Lab
Dr. Claydon is actively seeking graduate trainees at both the M.Sc. and Ph.D. levels. Please contact Dr. Claydon with inquiries.
Dr. Claydon’s research program is supported by funding from the following agencies:
- Taylor, CE et al.. 2021. Women in clinical autonomic research and the autonomic societies: how far have we come in thirty years?. Clin Auton Res. doi: 10.1007/s10286-021-00768-8.
- Dorton, MC et al.. 2020. Evaluation of cardiovascular disease risk in individuals with chronic spinal cord injury.. Spinal Cord. doi: 10.1038/s41393-020-00566-5.
- Lucci, VM et al.. 2020. Longitudinal Assessment of Autonomic Function during the Acute Phase of Spinal Cord Injury: Use of Low-Frequency Blood Pressure Variability as a Quantitative Measure of Autonomic Function.. J Neurotrauma. doi: 10.1089/neu.2020.7286.
- Shi, YP et al.. 2020. The hERG channel activator, RPR260243, enhances protective IKr current early in the refractory period reducing arrhythmogenicity in zebrafish hearts.. Am J Physiol Heart Circ Physiol. doi: 10.1152/ajpheart.00038.2020.
- Figueroa, JJ et al.. 2020. Autonomic function testing in the COVID-19 pandemic: an American Autonomic Society position statement.. Clin Auton Res. doi: 10.1007/s10286-020-00702-4.