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Dr. Piotr Kozlowski

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Principal Investigator

M.Sc. (Jagiellonian University), Ph.D. (Institute of Nuclear Physics)
Associate Director, Magnetic Resonance Imaging Research Centre, University of British Columbia
Associate Professor, Departments of Radiology and Urologic Sciences, Faculty of Medicine, University of British Columbia
Associate Member, Department of Physics and Astronomy, Faculty of Science, University of British Columbia
Research Scientist, Vancouver Prostate Centre

Research Interests

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Dr. Kozlowski’s research uses magnetic resonance imaging (MRI) based techniques to study SCI. He has worked on the development of a non-invasive technique for monitoring changes in myelin in the spinal cord following injury. Myelin in the brain and spinal cord helps neurons function more efficiently by wrapping around them, but it also inhibits healing when the neurons are injured. Studying how myelin changes after an injury may shed light on how to improve healing. Dr. Kozlowski also applies MRI and magnetic resonance spectroscopy technology to his prostate cancer research—his group has developed a novel MRI-based technique for diagnosing prostate cancer.

Dr. Kozlowski is an Associate Professor in the Departments of Radiology and Urologic Sciences at the University of British Columbia. He is a Principal Investigator at ICORD and Associate Director of the UBC Magnetic Resonance Imaging Research Centre. He is also an Associate Member of the Department of Physics and Astronomy at the University of British Columbia and a Research Scientist at the Vancouver Prostate Centre. Dr. Kozlowski obtained his M.Sc. at the Jagiellonian University and his Ph.D. at the Institute of Nuclear Physics in Krakow, Poland.

The technology that Dr. Kozlowski is developing can translate into improved models for research by allowing real-life assessment of new regeneration therapies. It can also further our understanding of the basic biology behind SCI.

Dr. Kozlowski values working at ICORD because of its excellent research environment. He is excited to have access to so many experts in the field of SCI research.

Dr. Kozlowski’s initial interest in physics was in the area of theoretical astrophysics and general theory of relativity. However, he quickly realized that working in an area closer to everyday life was more suitable for his future career, so he joined a group of physicists at the Institute of Nuclear Physics in Krakow, where he helped build the first research MRI scanner in Eastern Europe.

Recent Collaborations:

Dr. Kozlowski has been working with Dr. Wolfram Tetzlaff since 2004 on multiple projects including MRI techniques for studying white matter in the brain.

He has also worked with Dr. Tom Oxland on MRI techniques to recognize clinically relevant models of injury.

With Dr. Andrei Krassioukov, he has examined fat content in pre-SCI models and how this affects injury.

Major Findings:

In his work on prostate cancer, Dr. Kozlowski developed a diagnostic tool which combines two MRI techniques in order to detect tumours with greater sensitivity. He also determined that using MRI to detect a particular organic compound called EF5 is not suitable for assessing oxygen loss in prostate tumours. This helped clarify useful diagnostic techniques for detecting prostate cancer.

Myelin water mapping is a technique for measuring myelin content. Dr. Kozlowski demonstrated that myelin water mapping is possible in the spinal cord. This technique has the potential to be a valuable tool for studying myelin damage in spinal cord injuries. Dr. Kozlowski also developed an improved method of myelin water mapping which gives increased spatial detail.

For more of Dr. Kozlowski’s major findings, please see the selected publications below, as well as his recent publications listed at the bottom of the page:

Techniques employed in the lab:

  • Diffusion imaging
  • Dynamic Contrast Enhancement MRI
  • Magnetic resonance elastography
  • Magnetic resonance spectroscopy
  • Quantitative MRI

Affiliation with organizations and societies:

  • International Society for Magnetic Resonance in Medicine (ISMRM)
  • Associate Director, Magnetic Resonance Imaging Research Centre, University of British Columbia
  • Vancouver Prostate Centre (VPC)

Current Lab Members

Masters Students Ph.D. Students Postdoctoral Fellows Research Staff
Evan Chen* Vanessa Wiggermann Henry Chen Andrew Yung
Nadinee Fariah Haq* Jennifer Moroz
 Barry Bohnet Shirin Sabouri
Shahed Mohammed

*has graduated in the past year

Trainee Awards

Year Name Award
2013 Evan Chen Best Abstract by a Trainee at the 21st Annual Meeting of the ISMRM White Matter Study Group

Current Opportunities in the Lab

There are currently no openings in Dr. Kozlowski’s lab. Please contact Dr. Kozlowski with inquiries.

Recent publications

  • Stortz, G et al.. 2017. Performance of a PET Insert for High Resolution Small Animal PET/MR Imaging at 7T.. J. Nucl. Med. doi: 10.2967/jnumed.116.187666.
  • Mahdavi, SS et al.. 2017. Focal application of low-dose-rate brachytherapy for prostate cancer: a pilot study.. J Contemp Brachytherapy. doi: 10.5114/jcb.2017.68424.
  • Topping, GJ et al.. 2017. Manganese concentration mapping in the rat brain with MRI, PET, and autoradiography.. Med Phys. doi: 10.1002/mp.12300.
  • Sabouri, S et al.. 2017. Luminal Water Imaging: A New MR Imaging T2 Mapping Technique for Prostate Cancer Diagnosis.. Radiology. doi: 10.1148/radiol.2017161687.
  • Chen, HS, Holmes, N, Liu, J, Tetzlaff, W, Kozlowski, P. 2017. Validating myelin water imaging with transmission electron microscopy in a rat spinal cord injury model.. Neuroimage. doi: 10.1016/j.neuroimage.2017.03.065.
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