Hon. Leona Aglukkaq announces funding for cardiovascular health study

The Honourable Leona Aglukkaq, Federal Health Minister, was at the Blusson Spinal Cord Centre on Friday February 24th to announce new funding for research on cardiovascular health for people with SCI.

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Dr. Krassioukov, Dr. McMaster, Ms. Abbott-Peter, Dr. Feldman, Minister Aglukkaq

The team research project, led by ICORD Researcher Dr. Andrei Krassioukov, is entitled Improving cardiovascular health for Canadians living with spinal cord injury: Effects of exercise and targeted education. This project is supported by a grant from the Canadian Institutes of Health Research (CIHR). The team includes Dr. Krassioukov’s ICORD colleagues Drs. Janice Eng, Tania Lam and Matthew Ramer. The group will study the cardiovascular risks and effects of exercise training in people with SCI, as they respond differently to exercise. Another aspect of the study will involve educating health care providers on specific cardiovascular problems associated with SCI to help reduce the financial burden of care, and improve treatment, for people with SCI.

The Minister and Dr. Krassioukov were joined at the announcement by Dr. Howard Feldman, Associate Dean of Research for the UBC Faculty of Medicine, and Ms. Marni Abbott-Peter, a three-time Paralympic gold medallist in wheelchair basketball.

Click for more information about Dr. Krassioukov’s cardiovascular research.

Cardiovascular health and spinal cord injury: the surprising truth

Cardiovascular disease is the main cause of death in people with spinal cord injury (SCI), who develop the chronic disease at younger ages and greater rates than the able-bodied population.

This is a surprising fact — both for people who suffer a spinal cord injury, as well as their health caregivers, but a prestigious research grant promises to increase understanding and create healthier outcomes in this area. ICORD spinal cord research, Dr. Andrei Krassioukov has been awarded $1.9 million from the Canadian Institutes of Health Research to investigate how exercise and education can improve the cardiovascular health of Canadians living with SCI.  Dr. Krassioukov, who is an investigator with the ICORD spinal cord injury program at Vancouver Coastal Health Research Institute and the University of British Columbia as well as a physician at GF Strong Rehabilitation Centre and professor of Physical Medicine and Rehabilitation at UBC, will lead a team of 20 scientists, clinicians, and health care advocates from across both Canada and the United States to investigate the best ways to reduce chronic disease and improve cardiovascular health.

[For a complete list of researchers and institutions involved, click here.]

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(L - R) Dr. Andrei Krassioukov, research clinician with GF Strong Rehabilitation Centre and ICORD spinal cord research program at VCH Research Institute with Dean Stoney- working on cardiovascular health on an arm ergometer

“Twenty-years ago, I applied for my first grant to study the effect of spinal cord injury on the cardiovascular system, but it was widely believed that people with SCI didn’t need to worry about cardiovascular disease, and that the research community should focus on curing paralysis. While that is still the end goal, we now know how severe and life-threatening cardiovascular issues can be,” says Krassioukov. “With this grant we will study different types of exercise interventions as well as translating findings in such a way that we can educate health care providers on the specific cardiovascular problems that are associated with SCI. The results will be improved treatment for SCI as well as a reduction in the financial burden of care.”

One area the research team will be looking at is autonomic dysreflexia, which is a drastic increase in blood pressure striking those with cervical and upper thoracic injuries. If left untreated, it can lead to bleeding in the brain and or death.

This unstable blood pressure control is a concern to the general SCI population, but especially to athletes with SCI. Dr. Krassioukov led a major study during the 2010 Vancouver Paralympic games, and has received funding from the Craig Neilsen Foundation to run a cardiovascular health autonomic clinic in London’s Olympic Village.

Dr Krassioukov believes there needs to be much greater awareness of this issue. “With Paralympic athletes, we have two problems in this area,” says Krassioukov. “One is those who don’t know this is a risk and need crucial, practical information. The other is athletes who are aware of autonomic blood pressure spikes and will actually attempt to use it as a competitive advantage, which is extremely risky.”

The clinic in London will provide evidence-based clinical knowledge and crucial practical information on unstable arterial blood pressure control among athletes with SCI to Paralympians and their coaches at the 2012 Summer Games, and build on the research in this area.

“Understanding cardiovascular risks and the effects of exercise training in people with SCI has become vitally important,” said Dr. Jean Rouleau, Scientific Director of the CIHR Institute of Circulatory and Respiratory Health.  “This research will increase our understanding of how to design exercise programs specific to the individual, as we know that two people with the exact same spinal cord injury can respond quite differently to exercise intervention.”

Read more about this issue in Metro News.

Partner institutions:

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ICORD presents a symposium at AAAS

ICORD researchers will be joining with other eminent faculty from within Canada and the US to present Curing Spinal Cord Injury: The Need for Global Collaboration at the AAAS Annual Meeting in Vancouver. This meeting brings together approximately 8000 scientists from around the globe.

The symposium will take place on Monday, February 20, 2012: 9:45 AM-12:45 PM in Room 202-204 (VCC West Building). One-day registration is available for this event.

Spinal cord injury (SCI) remains an unsolved problem, exacting a tremendous burden on over 1.3 million injured people and their families in North America. Modern treatments for people with acute SCI have improved over the past 25 years, but there remains no cure for the injured spinal cord, and people living with SCI are confronted with significant medical complications secondary to the injury. This symposium will address the need for global collaboration to further improve the condition of people living with SCI and eventually develop cures. The critical role of basic science research to solve these complex problems will be emphasized, and the potential for stem cells in the treatment of SCI will be highlighted. The challenges in the clinical application of basic science discoveries will be presented along with a presentation of an exciting new spinal cord injury registry that promises to be a key research platform for the future. The application of novel therapies in this field brings up many ethical issues, and they will be discussed amidst the presentation of possible solutions for the global collaboration.

Organizer: Thomas R. Oxland, International Collaboration on Repair Discoveries, UBC/Vancouver Coastal Health
Co-Organizer: Michael Fehlings, Toronto Western Hospital
Speakers:
Charles Tator, University of Toronto The Importance of Basic Science: Filling the Pipeline
Wolfram Tetzlaff, ICORD, University of British Columbia /Vancouver Coastal Health Stem Cells: Are They the Solution?
Marcel Dvorak, ICORD, University of British Columbia /Vancouver Coastal Health The Challenge and Opportunity of Clinical Investigation in SCI
Judy Illes, University of British Columbia The Ethics of All This

Naomi Kleitman, NIH Global Cooperation and Support of SCI Research

ICORD Annual Research Meeting for 2012

logoICORD’s Annual Research Meeting for 2012 will take place at the Blusson Spinal Cord Centre on February 21st and 22nd. All ICORD PIs, Investigators, Associate Members, staff and trainees are encouraged to participate. Registration and abstract deadline is February 8th.

Contact admin@icord.org to request a registration form.

Café Scientifique will be webcast

wires-verticalIn response to requests from around the globe, ICORD’s first Café Scientifique event, Spinal cord injury research: it’s not rocket science, it’s harder, will be webcast (for both live-streaming and later viewing). Click here to join in or view the webcast.

We are excited to announce that the event is now booked to capacity. In order to make it an enjoyable evening for everyone, we cannot guarantee that we will be able to accommodate unregistered guests.

If you are registered but know you will be unable to attend, please email cafe@icord.org to let us know, as we have a considerable waiting list. Information about parking in the neighbourhood can be found here.

Students win at prestigious meeting

Congratulations to ICORD students Leanne Ramer and Greg Duncan, who both won Paralyzed Veterans of America Poster Awards at the 14th International Symposium on Neural Regeneration in Pacific Grove, California last week. Ms. Ramer is finishing her PhD with Drs. Andrei Krassioukov and John Steeves, and Mr. Duncan is a PhD student with Dr. Wolfram Tetzlaff.

ICORD Researcher receives funding from MS Society

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Congratulations to ICORD Principal Investigator Dr. Wayne Moore, who is a co-applicant on a recently-announced $3.8 million grant from the MS Society of Canada. Dr. Moore, who is a Clinical Professor in Pathology and Laboratory Medicine at UBC, researches MRI correlation in multiple sclerosis and neuropathology of spinal cord injury.


It’s not rocket science, it’s harder! A Café Scientifique event on January 19, 2012

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“Scientific breakthroughs” often appear in the news, yet we still have no cure for spinal cord injury. Join our expert panel of ICORD researchers for refreshments and lively discussion about how discoveries in the laboratory translate into treatments that affect lives now, as well as the inherent challenges in that process.

Speakers: Brian Kwon, MD, PhD • John Steeves, PhD • Andrei Krassioukov, MD, PhD • Bonita Sawatzky, PhD

7-9 pm, Thursday 19 January 2012
Blusson Spinal Cord Centre Atrium
No charge • Registration required.
RSVP to cafe@icord.org

Supported by CIHRFirefly Fine Wines and Ales The Lazy GourmetLonsdale Event Rentals

New blog highlights latest SCI research

dots-thumbICORD and the SCI Resource Centre are pleased to present SCRIBE, a new blog highlighting recent developments in SCI research at ICORD and around the world. This is a forum for SCI researchers to connect with the greater community. Check it out, and add your comments!

Upcoming Spinal Cord Injury conference

5th National Spinal Cord Injury Conference – Translating Neural Engineering and Novel Therapies

The 5th National SCI Conference organizing committee is putting together an exciting program featuring keynote addresses, podium and poster presentations, workshops and breakout sessions. Additional highlights include a hands-on pre-course, consumer participation and a delegate reception. You are invited to participate in the pre-eminent gathering of clinicians, research scientists and consumers in Canada and North America who are focused on understanding and achieving recovery among the spinal cord injury population.

Date: October 18-20, 2012

Location: Hilton Toronto, 145 Richmond Street West, Toronto (Oct 18th preconference at Toronto Rehab’s Lyndhurst Centre)

Abstract Deadline: March 4th, 2012 (by midnight)

More information? 416-597-3422 ext. 3693 / conferences@torontorehab.on.ca